0001193125-19-048943 Sample Contracts

AGREEMENT AND PLAN OF MERGER by and among ROCHE HOLDINGS, INC., 022019 MERGER SUBSIDIARY, INC. and SPARK THERAPEUTICS, INC. Dated as of February 22, 2019

Agreement and Plan of Merger • February 25th, 2019 • Spark Therapeutics, Inc. • Biological products, (no disgnostic substances) • Delaware

• Contract Type
  Agreement and Plan of Merger
• Filed
  February 25th, 2019
• Company
  Spark Therapeutics, Inc.
• Industry
  Biological products, (no disgnostic substances)
• Jurisdiction
  Delaware

THIS AGREEMENT AND PLAN OF MERGER (this “Agreement”) is made and entered into as of February 22, 2019, by and among: Roche Holdings, Inc., Delaware corporation (“Parent”); 022019 Merger Subsidiary, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”); and Spark Therapeutics, Inc., a Delaware corporation (the “Company”).