0001193125-19-092901 Sample Contracts

Chiasma, Inc. 6,315,790 Shares of Common Stock (par value $0.01 per share) Underwriting Agreement
Underwriting Agreement • March 29th, 2019 • Chiasma, Inc • Pharmaceutical preparations • New York

Chiasma, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of 6,315,790 shares of its common stock, par value $0.01 per share (the “Shares”). The 6,315,790 Shares to be sold by the Company are called the “Firm Shares.” In addition, the Company has granted to the Underwriters an option to purchase up to an additional 947,368 Shares, which are collectively called the “Option Shares.” The Firm Shares and, if and to the extent such option is exercised, the Option Shares, are collectively called the “Offered Shares.” Cantor Fitzgerald & Co. (“Cantor”) has agreed to act as representative of the several Underwriters (in such capacity, the “Representative”) in connection with the offering and sale of the Offered Shares. To the extent there are no additional underwriters listed on Schedule A, the term “Representative” as used herein shall mean Cantor, as Underwriter, and the term “Underwrite

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