0001193125-19-099438 Sample Contracts

SYROS PHARMACEUTICALS, INC. 8,667,333 shares of common stock, par value $0.001 per share (the “Common Stock”) and Class A Warrants to Purchase up to 1,951,844 Shares of Common Stock Underwriting Agreement
Underwriting Agreement • April 8th, 2019 • Syros Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

Syros Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), (i) an aggregate of 8,667,333 shares of Common Stock of the Company (the “Shares”) and (ii) Class A Warrants, substantially in the form of Exhibit A hereto, to purchase an aggregate of 1,951,844 shares of Common Stock (the “Warrants,” such Shares and Warrants to be issued and sold by the Company being hereinafter collectively called the “Securities”). Each share was offered by the Company together with a Warrant to purchase one-quarter of one share of Common Stock at an exercise price of $8.625 per whole share; provided, that 859,957 of the Shares to be sold hereunder are being sold without such Warrants. As used herein, “Warrant Shares” means the shares of Common Stock issuable upon exercise of the Warrants. The shares of Common Stock of the Compa

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