0001193125-19-211417 Sample Contracts

SUBSCRIPTION AGREEMENT
Subscription Agreement • August 2nd, 2019 • Constellation Alpha Capital Corp. • Services-medical laboratories • New York

In connection with the proposed business combination (the “Transaction”) in which DermTech, Inc., a Delaware Corporation (“DermTech”) will merge with a wholly-owned subsidiary corporation of Constellation Alpha Capital Corp., a company incorporated in the British Virgin Islands and which is expected to re-domicile in the State of Delaware (the “Company”), the undersigned desires to subscribe for and purchase from the Company, and the Company desires to sell to the undersigned, that number of shares of common stock (the “Company Shares”) of the Company set forth on the signature page hereof for a purchase price of $3.25 per share, on the terms and subject to the conditions contained herein. In connection therewith, the undersigned and the Company agree as follows:

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FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER
Agreement and Plan of Merger • August 2nd, 2019 • Constellation Alpha Capital Corp. • Services-medical laboratories • Delaware

This FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER, dated as of August 1, 2019 (this “Amendment”), is entered into by and among Constellation Alpha Capital Corp., a company incorporated in the British Virgin Islands (“Constellation”), DT Merger Sub, Inc., a Delaware corporation (“Merger Sub”), and DermTech, Inc., a Delaware corporation (the “Company” and together with Constellation and Merger Sub, the “Parties”).

OMNIBUS COMMON SHARE SUBSCRIPTION AGREEMENT AMENDMENT
Omnibus Common Share Subscription Agreement Amendment • August 2nd, 2019 • Constellation Alpha Capital Corp. • Services-medical laboratories • New York

This OMNIBUS COMMON SHARE SUBSCRIPTION AGREEMENT AMENDMENT (this “Amendment”) is made and entered into as of August 1, 2019, by and among Constellation Alpha Capital Corp., a company incorporated in the British Virgin Islands (the “Company”) and certain Purchasers listed on Schedule A hereto (the “Common Share Purchasers”).

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