0001193125-20-080654 Sample Contracts

FIRST AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 20th, 2020 • Orchard Therapeutics PLC • Biological products, (no disgnostic substances) • Massachusetts

This First Amendment to Employment Agreement (this “Amendment”) is entered into and effective as of March 18, 2020 (the “Effective Date”), by and between Orchard Therapeutics plc (the “Parent”), Orchard Therapeutics North America, a California corporation (the “U.S. Subsidiary”) and Frank Thomas (the “Executive”). The Parent, the U.S. Subsidiary and their respective subsidiaries and other affiliates are collectively referred to herein as the “Company,” and the duties of the Company as set forth in this Amendment may be discharged by any entity within that definition.

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DATED 17 MARCH 2020
Settlement Agreement • March 20th, 2020 • Orchard Therapeutics PLC • Biological products, (no disgnostic substances) • England and Wales
SEPARATION AGREEMENT AND RELEASE
Separation Agreement • March 20th, 2020 • Orchard Therapeutics PLC • Biological products, (no disgnostic substances) • Massachusetts

This Separation Agreement and Release (“Agreement”) is made between Orchard Therapeutics plc (the “Parent”), Orchard Therapeutics North America, a California corporation (the “U.S. Subsidiary”) and Mark Rothera (the “Executive”). The Parent, the U.S. Subsidiary and their respective subsidiaries and other affiliates are collectively referred to herein as the “Company,” and the obligations of the Company set forth in this Agreement may be discharged by any entity within that definition. The Parent, the U.S. Subsidiary and the Executive are collectively referred to as the “Parties.”

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