0001193125-20-108419 Sample Contracts

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON AND IMMATICS US, INC. AMENDMENT NUMBER 2 — FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V.

This Amendment Number 2 (“Amendment”) to the Facilities/Equipment Use and Services Agreement effective September 1, 2015 by and between The University of Texas Health Science Center at Houston, (“UTHealth”) and lmmatics US, Inc. (“lmmatics”), as amended (“Agreement”) is entered into effective the 101h day of August 2016,. UTHealth and Immatics shall be known collectively as “the Parties” and singularly as “a Party” or “the Party.”

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MASTER CLINICAL TRIAL AGREEMENT
Master Clinical Trial Agreement • April 16th, 2020 • Immatics B.V. • Texas

This Master Clinical Trial Agreement (this “Agreement”) is entered into as of December 1, 2016 (the “Effective Date”), by and between Immatics US, Inc. (“Sponsor”), having a principal place of business at 2130 Holcombe, Suite 11.3000, Houston, Texas 77030 and The University of Texas MD Anderson Cancer Center (“Study Site”), an agency of the State of Texas and a member institution of The University of Texas System (“System”), located at 1515 Holcombe Blvd., Houston, Texas 77030. Sponsor and the Study Site are sometimes referred to herein individually as a “Party” and collectively as “Parties.”

IMMATICS US, INC. RESTRICTED STOCK ACQUISITION AGREEMENT
Restricted Stock Purchase Agreement • April 16th, 2020 • Immatics B.V. • Delaware

THIS RESTRICTED STOCK PURCHASE AGREEMENT (the “Agreement”) is made as of the 14th day of August, 2015, by and among IMMATICS US, INC., a Delaware corporation (the “Company”), the Board of Regents of the University of Texas System, for the benefit of the University of Texas M.D. Anderson Cancer Center, a member institution of The University of Texas System and an agency of the State of Texas (“MD Anderson”), and IMMATICS BIOTECHNOLOGIES GMBH (the “Parent”) (solely with respect to terms and conditions set forth under Sections 1(d), 2, 5, 9 and 10).

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON AND IMMATICS US, INC. AMENDMENT NUMBER 1 – FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V.

This Amendment Number 1 (“Amendment”) to the Facilities/Equipment Use and Services Agreement (“Agreement”) is entered into effective the 1st day of September 2015, by and between The University of Texas Health Science Center at Houston, (“UTHealth”) and Immatics US, Inc. (“Immatics”). UTHealth and Immatics shall be known collectively as “the Parties” and singularly as “a Party” or “the Party.”

THE SYMBOL “[***]” DENOTES PLACES WHERE CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THE EXHIBIT BECAUSE IT IS BOTH (i) NOT MATERIAL, AND (ii) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF PUBLICLY DISCLOSED
License Royalty Adjustment Agreement • April 16th, 2020 • Immatics B.V.

This License Royalty Adjustment Agreement (“Agreement”) is made on this 5th day of January, 2016, by and between THE BOARD OF REGENTS (“Board”) of THE UNIVERSITY OF TEXAS SYSTEM (“System”), an agency of the State of Texas, whose address is 201 West 7th Street, Austin, Texas 78701, on behalf of THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER (“UTMDACC”), a member institution of SYSTEM, and IMMATICS US, INC., a Delaware corporation having a principal place of business located at 700 Milam Street, Suite 1300, Houston, Texas 77002 USA (“Licensee”).

COLLABORATION & LICENSE AGREEMENT
Collaboration & License Agreement • April 16th, 2020 • Immatics B.V. • Texas

This COLLABORATION & LICENSE AGREEMENT (this “Agreement”) is entered into as of August 17, 2015 (the “Effective Date”) by and between IMMATICS US INC., a corporation organized and existing under the laws of Delaware (“Immatics US”) and The University of Texas M. D. Anderson Cancer Center, (“MD Anderson”), a member institution of The University of Texas System (“System”), with a place of business at 1515 Holcombe Blvd., Houston, Texas. Immatics US and MD Anderson are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON AND IMMATICS US, INC. AMENDMENT NUMBER 5 — FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V.

This Amendment Number 5 (“Amendment”) to the Facilities/Equipment Use and Services Agreement (“Agreement”) is entered into effective the 1st day of July 2018, by and between The University of Texas Health Science Center at Houston, (“UTHealth”) and Immatics US, Inc. (“Immatics”). UTHealth and Immatics shall be known collectively as ‘the Parties” and singularly as “a Party” or “the Party.”

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON AND IMMATICS US, INC. AMENDMENT NUMBER 3 – FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V.

This Amendment Number 3 (“Amendment”) to the Facilities/Equipment Use and Services Agreement (“Agreement”) is entered into effective the 1st day of October 2016, by and between The University of Texas Health Science Center at Houston, (“UTHealth”) and Immatics US, Inc. (“Immatics”). UTHealth and Immatics shall be known collectively as “the Parties” and singularly as “a Party” or “the Party.”

FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V. • Texas

THIS FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT (“Agreement”), dated effective as of September 1, 2015 (“Effective Date”), is made and entered into by and between The University of Texas Health Science Center at Houston (“UTHealth”), an institution of The University of Texas System and governed by the Board of Regents (“Board”) and Immatics US, Inc., a Delaware corporation (“Immatics”).

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON AND IMMATICS US, INC. AMENDMENT NUMBER 4 — FACILITIES/EQUIPMENT USE AND SERVICES AGREEMENT
Facilities/Equipment Use and Services Agreement • April 16th, 2020 • Immatics B.V.

This Amendment Number 4 (“Amendment”) to the Facilities/Equipment Use and Services Agreement (“Agreement”) is entered into effective the 1st day of April 2017, by and between The University of Texas Health Science Center at Houston, (“UTHealth”) and Immatics US, Inc. (“Immatics”). UTHealth and Immatics shall be known collectively as “the Parties” and singularly as “a Party” or “the Party.”

NON-EXCLUSIVE LICENSE AGREEMENT
License Agreement • April 16th, 2020 • Immatics B.V.

STICHTING SANQUIN BLOEDVOORZIENING, a foundation organized and existing under the laws of the Netherlands, having its address at Plesmanlaan 125, 1066 CX Amsterdam, the Netherlands (“SANQUIN”);

FORM OF SUBSCRIPTION AGREEMENT
Subscription Agreement • April 16th, 2020 • Immatics B.V.

In connection with the proposed business combination (the “Transaction”) between ARYA Sciences Acquisition Corp., a Cayman Islands exempted company (“ARYA”), and Immatics Biotechnologies GmbH, a limited liability company (Gesellschaft mit beschränkter Haftung) organized under the laws of Germany (“Immatics”), pursuant to a business combination agreement to be entered into among Immatics, Immatics B.V., a Netherlands private company with limited liability company (besloten vennootschap met beperkte aansprakelijkheid) and a newly formed entity formed for the purpose of consummating the Transaction (the “Company”), and the other parties thereto (the “Transaction Agreement”), the Company is seeking commitments from interested investors to purchase ordinary shares, par value EUR 0.01 per share (the “Shares”), of the Company, for a purchase price of $10.00 per share. The aggregate purchase price to be paid by the undersigned (the “Investor”) for the subscribed Shares (as set forth on the sig

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