AMENDMENT NO. 1 TO THE OPEN MARKET SALE AGREEMENTSMConcert Pharmaceuticals, Inc. • November 5th, 2020 • Pharmaceutical preparations • New York
Company FiledNovember 5th, 2020 Industry JurisdictionThis Amendment No. 1 to the Open Market Sale AgreementSM (this “Amendment”) is entered into as of the date first written above by Concert Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Jefferies LLC (the “Agent”), that are parties to that certain Open Market Sale AgreementSM, dated March 1, 2019 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement as follows: