0001193125-21-000946 Sample Contracts

•] Shares PRELUDE THERAPEUTICS INCORPORATED COMMON STOCK (PAR VALUE $0.0001 PER SHARE) UNDERWRITING AGREEMENT
Underwriting Agreement • January 4th, 2021 • Prelude Therapeutics Inc • Pharmaceutical preparations • New York
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REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • January 4th, 2021 • Prelude Therapeutics Inc • Pharmaceutical preparations • New York

This Registration Rights Agreement (this “Agreement”) is made as of [ ], 2020 by and between Prelude Therapeutics Incorporated, a Delaware corporation (the “Company”), and the persons listed on the attached Schedule A who are signatories to this Agreement (collectively, the “Investors”). Unless otherwise defined herein, capitalized terms used in this Agreement have the respective meanings ascribed to them in Section 1.

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • January 4th, 2021 • Prelude Therapeutics Inc • Pharmaceutical preparations • Delaware

This Executive Employment Agreement (the “Agreement”), made between Prelude Therapeutics Incorporated, a Delaware corporation (the “Company”), and Christopher Pierce (“Executive” and, collectively with the Company, the “Parties”), is entered into as of December 19, 2020 (the “Effective Date”).

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • January 4th, 2021 • Prelude Therapeutics Inc • Pharmaceutical preparations • Delaware

This Executive Employment Agreement (the “Agreement”), made between Prelude Therapeutics Incorporated, a Delaware corporation (the “Company”), and Krishna Vaddi (“Executive” and, collectively with the Company, the “Parties”), is entered into as of December 30, 2020 (the “Effective Date”).

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