0001193125-21-044891 Sample Contracts

Contract
Biogen Inc. • February 16th, 2021 • Biological products, (no disgnostic substances) • New York

THIS NOTE IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), OR A NOMINEE OF DTC. THIS NOTE IS EXCHANGEABLE FOR NOTES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC, BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC OR BY DTC OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH A SUCCESSOR DEPOSITARY.

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BIOGEN INC., as Issuer and U.S. Bank National Association, as Trustee Third Supplemental Indenture Dated as of February 16, 2021
Biogen Inc. • February 16th, 2021 • Biological products, (no disgnostic substances) • New York

SUPPLEMENTAL INDENTURE (this “Third Supplemental Indenture”), dated as of February 16, 2021, between BIOGEN INC., a Delaware corporation (the “Company”), and U.S. Bank National Association, a national association, as Trustee (the “Trustee”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • February 16th, 2021 • Biogen Inc. • Biological products, (no disgnostic substances) • New York

This REGISTRATION RIGHTS AGREEMENT dated February 16, 2021 (this “Agreement”) is entered into by and among Biogen Inc., a Delaware corporation (the “Company”), and Deutsche Bank Securities Inc. and Citigroup Global Markets Inc. as dealer managers (each, a “Dealer Manager” and, together, the “Dealer Managers”).

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