0001193125-21-063387 Sample Contracts

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • March 1st, 2021 • Ziopharm Oncology Inc • Pharmaceutical preparations • Massachusetts

AMENDMENT TO EMPLOYMENT AGREEMENT (the “Amendment”), dated as of November 23, 2020 (the “Effective Date”), by and between ZIOPHARM Oncology, Inc., a Delaware corporation (the “Company”), and Sath Shukla (the “Employee”). Capitalized terms used herein and not otherwise defined shall have the meanings ascribed to them in the Employment Agreement (as defined below).

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FIRST AMENDMENT TO LEASE AGREEMENT
Lease Agreement • March 1st, 2021 • Ziopharm Oncology Inc • Pharmaceutical preparations • Texas

This First Amendment to Lease Agreement (“First Amendment”) is made effective as of April 7, 2020 (“Effective Date”), by and between the Board of Regents of The University of Texas System (“Landlord”) and Ziopharm Oncology, Inc., a Delaware corporation (“Tenant”).

ZIOPHARM ONCOLOGY, INC. FORM OF STOCK OPTION AGREEMENT
Form of Stock Option Agreement • March 1st, 2021 • Ziopharm Oncology Inc • Pharmaceutical preparations

As reflected by your Stock Option Grant Notice (“Grant Notice”) ZIOPHARM Oncology, Inc. (the “Company”) has granted you an option under its 2020 Equity Incentive Plan (the “Plan”) to purchase a number of shares of Common Stock at the exercise price indicated in your Grant Notice (the “Option”). Capitalized terms not explicitly defined in this Agreement but defined in the Grant Notice or the Plan shall have the meanings set forth in the Grant Notice or Plan, as applicable. The terms of your Option as specified in the Grant Notice and this Stock Option Agreement constitute your Option Agreement.

THIRD AMENDMENT TO LEASE
Lease • March 1st, 2021 • Ziopharm Oncology Inc • Pharmaceutical preparations

This Third Amendment to Lease (this “Amendment”), is made as of the 15th day of December, 2020 (the “Effective Date”), by and between the BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, acting for the use and benefit of The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System (“Landlord”) and ZIOPHARM ONCOLOGY, INC., a Delaware corporation (“Tenant”).

ZIOPHARM ONCOLOGY, INC. FORM OF RESTRICTED STOCK AGREEMENT
Ziopharm Oncology Inc • March 1st, 2021 • Pharmaceutical preparations

Pursuant to the Restricted Stock Grant Notice (“Grant Notice”) and this Restricted Stock Agreement (collectively, the “Award”) and [in consideration of your past services], ZIOPHARM Oncology, Inc. (the “Company”) has granted you a Restricted Stock Award under its 2020 Equity Incentive Plan (the “Plan”) for the number of shares of Common Stock subject to the Award as indicated in the Grant Notice. Capitalized terms not explicitly defined in this Restricted Stock Agreement but defined in the Grant Notice or the Plan shall have the meanings set forth in the Grant Notice or Plan, as applicable. The terms of your Restricted Stock Award as specified in the Grant Notice and this Restricted Stock Agreement, including attachments thereto, constitute your Award Agreement.

SECOND AMENDMENT TO LEASE
Lease • March 1st, 2021 • Ziopharm Oncology Inc • Pharmaceutical preparations
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