CRINETICS PHARMACEUTICALS, INC. 4,562,044 Shares of Common Stock, par value $0.001 per share Underwriting AgreementCrinetics Pharmaceuticals, Inc. • April 8th, 2021 • Pharmaceutical preparations • New York
Company FiledApril 8th, 2021 Industry JurisdictionCrinetics Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), an aggregate of 4,562,044 shares of common stock, par value $0.001 per share (“Common Stock”), of the Company (the “Underwritten Shares”). The Underwritten Shares are herein referred to as the “Shares”. The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock”. For purposes of this underwriting agreement (this “Agreement”), the term Representatives as used herein shall mean SVB Leerink LLC and shall mean the singular and, if there are no other underwriters listed in Schedule 1, the term Underwriters as used herein shall mean SVB Leerink LLC and shall mean the singular.