0001193125-21-308118 Sample Contracts

ASSIGNMENT AGREEMENT BETWEEN HERLEV AND GENTOFTE HOSPITAL AND IO BIOTECH ApS
IO Biotech, Inc. • October 26th, 2021 • Pharmaceutical preparations

have entered into this assignment agreement regarding the assignment by the Hospital to the Company of certain intellectual property rights on the terms and conditions set out in the following.

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OPTION ASSIGNMENT AGREEMENT between IO Biotech ApS and Herlev Hospital
Option Assignment Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations

THIS OPTION ASSIGNMENT AGREEMENT (this “Agreement”) shall come into force and be effective as of the Effective Date as defined below, cf. Clause 1, and is entered into by and between

2nd AMENDMENT TO OPTION ASSIGNMENT AGREEMENT BETWEEN HERLEV AND GENTOFTE HOSPITAL AND IO BIOTECH ApS (Assignment of Arginase 1)
Option Assignment Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations

have entered into this amendment to the assignment agreement entered into between the Parties on 27 March 2017 regarding the grant by the Hospital to the Company of an option to acquire certain intellectual property rights.

CLINICAL TRIAL COLLABORATION AND SUPPLY AGREEMENT by and among MSD International GmbH, MSD International Business GmbH, and IO Biotech ApS
Clinical Trial Collaboration and Supply Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations • New York

This CLINICAL TRIAL COLLABORATION AND SUPPLY AGREEMENT (this “Agreement”), is entered into as of the date of last signature hereunder (the “Effective Date”), by and among MSD International GmbH (“MSDIG”), MSD International Business GmbH (“MSDIB” and collectively with MSDIG, “MSD”), having a place of business at [***] and IO Biotech ApS, having a place of business at [***] (“Company”). MSD and Company are each referred to herein individually as “Party” and collectively as “Parties”.

Addendum to Service Agreement
Service Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations
FRAMEWORK ASSIGNMENT AGREEMENT BETWEEN HERLEV HOSPITAL AND IO BIOTECH ApS
IO Biotech, Inc. • October 26th, 2021 • Pharmaceutical preparations

have entered into a framework assignment agreement regarding the potential assignment from the Hospital to the Company of intellectual property rights and title in and to certain inventions which may be made by the Hospital or any of its employees on the terms and conditions set out in this framework assignment agreement.

Execution version Agreement on Payment for Specific Services IO Biotech ApS and Herlev og Gentofte Hospital
IO Biotech, Inc. • October 26th, 2021 • Pharmaceutical preparations

(such agreements together with any other agreements and understandings between the Parties in force as of the date of this Agreement hereinafter collectively referred to as the “Principal Agreements”);

Service Agreement
Service Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations
1st AMENDMENT TO OPTION ASSIGNMENT AGREEMENT BETWEEN HERLEV AND GENTOFTE HOSPITAL AND IO BIOTECH ApS (1st amendment to Option Assignment Agreement of Arginase 1)
IO Biotech, Inc. • October 26th, 2021 • Pharmaceutical preparations

have entered into this amendment to the assignment agreement entered into between the Parties on 27 March 2017 regarding the grant by the Hospitals to the Company of an option to acquire certain intellectual property rights.

ADDENDUM I TO OPTION ASSIGNMENT AGREEMENT between IO Biotech ApS and Herlev Hospital
Option Assignment Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations
Addendum to Service Agreement
Service Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations
Execution version Service Agreement IO Biotech ApS – Mai-Britt Zocca
Service Agreement • October 26th, 2021 • IO Biotech, Inc. • Pharmaceutical preparations
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