FREELINE THERAPEUTICS HOLDINGS PLC (a public limited company organized under the laws of England and Wales) 24,857,144 American Depositary Shares Representing an Aggregate of 24,857,144 Ordinary Shares PURCHASE AGREEMENTPurchase Agreement • March 15th, 2022 • Freeline Therapeutics Holdings PLC • Biological products, (no disgnostic substances) • New York
Contract Type FiledMarch 15th, 2022 Company Industry JurisdictionFreeline Therapeutics Holdings plc, a public limited company organized under the laws of England and Wales (the “Company”), confirms its agreement with each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”), with respect to the issuance and sale by the Company and the purchase by the Purchasers, severally and not jointly, of an aggregate of 24,857,144 American Depositary Shares of the Company (“ADSs”), each ADS representing one ordinary share, nominal value £0.00001 per share, of the Company (“Ordinary Shares”). The new Ordinary Shares represented by the ADSs are herein called the “Shares.”