0001193125-22-172083 Sample Contracts

PREFERRED SHARES RIGHTS AGREEMENT Dated as of June 9, 2022 between ZYMEWORKS INC. and COMPUTERSHARE TRUST COMPANY, N.A., as Rights Agent

Preferred Shares Rights Agreement • June 10th, 2022 • Zymeworks Inc. • Pharmaceutical preparations • Delaware

• Contract Type
  Preferred Shares Rights Agreement
• Filed
  June 10th, 2022
• Company
  Zymeworks Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

This Preferred Shares Rights Agreement (this “Agreement”), dated as of June 9, 2022, is between Zymeworks Inc., a corporation continued under the Business Corporations Act (British Columbia) (the “Company”), and Computershare Trust Company, N.A., a United States federally chartered trust company, as rights agent (the “Rights Agent”). Each of the Company and the Rights Agent are sometimes referred to as a “Party.” All capitalized terms used in this Agreement have the meanings given to them in Section 1.