0001193125-22-175176 Sample Contracts

Day One Biopharmaceuticals, Inc. 10,000,000 Shares of Common Stock, par value $0.0001 per share Underwriting Agreement
Day One Biopharmaceuticals, Inc. • June 16th, 2022 • Pharmaceutical preparations • New York

Day One Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom J.P. Morgan Securities LLC (“JPM”), Cowen and Company, LLC (“Cowen”) and Piper Sandler & Co. (“Piper”) are acting as representatives (the “Representatives”), an aggregate of 10,000,000 shares of common stock, par value $0.0001 per share (“Common Stock”), of the Company (the “Underwritten Shares”) and, at the option of the Underwriters, up to an additional 1,500,000 shares of Common Stock of the Company (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares”. The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock”.

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