0001193125-22-186433 Sample Contracts

89BIO, INC. (a Delaware corporation) 18,675,466 Shares of Common Stock 7,944,252 Pre-Funded Warrants to Purchase 7,944,252 Shares of Common Stock 26,619,718 Common Warrants to Purchase 13,309,859 Shares of Common Stock UNDERWRITING AGREEMENT

Underwriting Agreement • July 1st, 2022 • 89bio, Inc. • Pharmaceutical preparations • New York

• Contract Type
  Underwriting Agreement
• Filed
  July 1st, 2022
• Company
  89bio, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

COMMON STOCK PURCHASE WARRANT 89bio, Inc.

Common Stock Purchase Warrant • July 1st, 2022 • 89bio, Inc. • Pharmaceutical preparations

• Contract Type
  Common Stock Purchase Warrant
• Filed
  July 1st, 2022
• Company
  89bio, Inc.
• Industry
  Pharmaceutical preparations

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Issue Date”) and on or prior to 5:00 p.m. (New York City time) on July 1, 2024, (the “Termination Date”) but not thereafter, to subscribe for and purchase from 89bio, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of common stock, $0.001 par value per share, of the Company (“Common Stock”). The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).