FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENTLoan and Security Agreement • April 6th, 2023 • Gritstone Bio, Inc. • Biological products, (no disgnostic substances) • California
Contract Type FiledApril 6th, 2023 Company Industry JurisdictionTHIS FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Amendment”), dated as of March 31, 2023 (the “Amendment Effective Date”), is entered into by and among Gritstone Bio, Inc., a Delaware corporation, and each of its Subsidiaries party hereto as borrower (hereinafter collectively referred to as the “Borrower””), and Silicon Valley Bank, a division of First-Citizens Bank & Trust Company (successor by purchase to the Federal Deposit Insurance Corporation as Receiver for Silicon Valley Bridge Bank, N.A. (as successor to Silicon Valley Bank)) (“SVB”), HERCULES CAPITAL, INC., a Maryland corporation (“Hercules”), and HERCULES CAPITAL FUNDING TRUST 2022-1, each as a Lender (collectively, with the several banks and other financial institutions or entities from time to time party to the Loan and Security Agreement (as defined below), the “Lenders”), and Hercules, in its capacity as administrative agent and collateral agent for itself and the Lenders (in such capacity, together with its su