0001193125-23-289224 Sample Contracts

AMENDMENT NO. 1 TO THE SALES AGREEMENT
The Sales Agreement • December 5th, 2023 • Disc Medicine, Inc. • Pharmaceutical preparations

This Amendment No. 1 to the sales agreement (this “Amendment No. 1”) is entered into as of the date first written above by Disc Medicine, Inc., a Delaware corporation (the “Company”), and Jefferies LLC (the “Agent”), that are parties to that certain sales agreement, dated October 10, 2023 (the “Sales Agreement”) relating to the offering of up to $59,700,000 of the Company’s Common Shares (the “Original Offering Amount”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Sales Agreement.

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