0001193125-24-018812 Sample Contracts

FORM OF CONTINGENT VALUE RIGHTS AGREEMENT
Contingent Value Rights Agreement • January 30th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS CONTINGENT VALUE RIGHTS AGREEMENT (this “Agreement”), dated as of [_____], 2024, is entered into by and among AVROBIO, Inc., a Delaware corporation (the “Company”) and [_____], a [_____] corporation (“Rights Agent”).

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FORM OF LOCK-UP AGREEMENT
Lock-Up Agreement • January 30th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances)

The undersigned signatory of this lock-up agreement (this “Lock-Up Agreement”) understands that AVROBIO, Inc., a Delaware corporation (“Aspen”), is entering into an Agreement and Plan of Merger, dated as of January 30, 2024 (as the same may be amended from time to time, the “Merger Agreement”) with Alpine Merger Subsidiary, Inc., a Delaware corporation and a wholly owned subsidiary of Aspen, and Tectonic Therapeutic, Inc., a Delaware corporation (the “Company”). Capitalized terms used but not otherwise defined herein shall have the respective meanings ascribed to such terms in the Merger Agreement.

FORM OF COMPANY STOCKHOLDER SUPPORT AGREEMENT
Company Stockholder Support Agreement • January 30th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Delaware

This Support Agreement (this “Agreement”) is made and entered into as of January 30, 2024, by and among Tectonic Therapeutic, Inc., a Delaware corporation (the “Company”), AVROBIO, Inc., a Delaware corporation (“Aspen”), and the undersigned stockholder (the “Stockholder”) of the Company. Capitalized terms used herein but not otherwise defined shall have the respective meanings ascribed to such terms in the Merger Agreement (as defined below).

FORM OF ASPEN STOCKHOLDER SUPPORT AGREEMENT
Stockholder Support Agreement • January 30th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Delaware

This Support Agreement (this “Agreement”) is made and entered into as of January 30, 2024, by and among Tectonic Therapeutic, Inc., a Delaware corporation (the “Company”), AVROBIO, Inc., a Delaware corporation (“Aspen”), and the undersigned stockholder (the “Stockholder”) of Aspen. Capitalized terms used herein but not otherwise defined shall have the respective meanings ascribed to such terms in the Merger Agreement (as defined below).

AGREEMENT AND PLAN OF MERGER AND REORGANIZATION among: AVROBIO, INC.; ALPINE MERGER SUBSIDIARY, INC.; and TECTONIC THERAPEUTIC, INC. Dated as of January 30, 2024
Merger Agreement • January 30th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS AGREEMENT AND PLAN OF MERGER AND REORGANIZATION (this “Agreement”) is made and entered into as of January 30, 2024, by and among AVROBIO, Inc., a Delaware corporation (“Aspen”), ALPINE MERGER SUBSIDIARY, INC., a Delaware corporation and wholly owned subsidiary of Aspen (“Merger Sub”), and TECTONIC THERAPEUTIC, INC., a Delaware corporation (the “Company”). Certain capitalized terms used in this Agreement are defined in Section 1.

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