0001193125-24-040017 Sample Contracts

CARDINAL HEALTH, INC. UNDERWRITING AGREEMENT February 14, 2024
Underwriting Agreement • February 20th, 2024 • Cardinal Health Inc • Wholesale-drugs, proprietaries & druggists' sundries • New York

The Securities will be issued pursuant to the indenture (the “Base Indenture”), dated as of June 2, 2008, between the Company and The Bank of New York Mellon Trust Company, N.A., as trustee (the “Trustee”), as supplemented by the First Supplemental Indenture (together with the Base Indenture, the “Indenture”), dated as of February 20, 2024, between the Company and the Trustee. If the firm or firms listed in Schedule II hereto include only the firm or firms listed in Schedule I hereto, then the terms “Underwriters” and “Representatives,” as used herein, shall each be deemed to refer to such firm or firms.

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CARDINAL HEALTH, INC. and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of February 20, 2024 to INDENTURE Dated as of June 2, 2008 5.125% Notes due 2029 5.450% Notes due 2034
First Supplemental Indenture • February 20th, 2024 • Cardinal Health Inc • Wholesale-drugs, proprietaries & druggists' sundries • New York

FIRST SUPPLEMENTAL INDENTURE, dated as of February 20, 2024 (the “First Supplemental Indenture”), between Cardinal Health, Inc., an Ohio corporation (the “Issuer”), and The Bank of New York Mellon Trust Company, N.A., a national banking association duly incorporated and existing under the laws of the United States of America, as trustee (the “Trustee”).

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