0001193125-24-074566 Sample Contracts

LYRA THERAPEUTICS, INC. Shares of Common Stock (par value $0.001 per share) Amended and Restated Controlled Equity OfferingSM Sales Agreement
Lyra Therapeutics, Inc. • March 22nd, 2024 • Surgical & medical instruments & apparatus • New York

Lyra Therapeutics, Inc., a Delaware corporation (the “Company”), and Cantor Fitzgerald & Co. (the “Agent”), are parties to that certain Sales Agreement dated September 1, 2023 (the “Original Agreement”). The Company and the Agent desire to amend and restate the Original Agreement in its entirety as set forth in this Amended and Restated Sales Agreement (this “Agreement”).

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