0001193125-24-091936 Sample Contracts

AGREEMENT AND PLAN OF MERGER DATED AS OF APRIL 10, 2024, AMONG VERTEX PHARMACEUTICALS INCORPORATED, ADAMS MERGER SUB, INC. AND ALPINE IMMUNE SCIENCES, INC.
Merger Agreement • April 10th, 2024 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • Delaware

This AGREEMENT AND PLAN OF MERGER, dated as of April 10, 2024 (this “Agreement” and, such date, the “Agreement Date”), by and among Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (“Parent”), Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”), and Alpine Immune Sciences, Inc., a Delaware corporation (the “Company”).

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TENDER AND SUPPORT AGREEMENT
Tender and Support Agreement • April 10th, 2024 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • Delaware

This TENDER AND SUPPORT AGREEMENT (this “Agreement”), dated as of April 10, 2024, is entered into by and among Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (“Parent”), Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”), each of the stockholders of Alpine Immune Sciences, Inc., a Delaware corporation (“Company”), set forth on Schedule A hereto (each, a “Stockholder” and, collectively, the “Stockholders”) and, solely for purposes of Section 1.1, the Company. All terms used but not otherwise defined in this Agreement shall have the respective meanings ascribed to such terms in the Merger Agreement (as defined below).

Vertex Enters Into Agreement to Acquire Alpine Immune Sciences - Alpine is a clinical stage biotechnology company focused on discovering and developing innovative, protein-based immunotherapies - - Alpine’s lead product, povetacicept, demonstrated...
Acquisition Agreement • April 10th, 2024 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations

BOSTON and SEATTLE (BUSINESS WIRE) – April 10, 2024—Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Alpine Immune Sciences, Inc. (Nasdaq: ALPN), a biotechnology company focused on discovering and developing innovative, protein-based immunotherapies, today announced that the companies have entered into a definitive agreement under which Vertex will acquire Alpine for $65 per share or approximately $4.9 billion in cash. The transaction was unanimously approved by both the Vertex and Alpine Boards of Directors and is anticipated to close later this quarter.

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