0001193125-24-223695 Sample Contracts

LABORATORY CORPORATION OF AMERICA HOLDINGS, as Issuer AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, as Trustee INDENTURE DATED AS OF SEPTEMBER 23, 2024 SENIOR DEBT SECURITIES
Indenture • September 23rd, 2024 • Labcorp Holdings Inc. • Services-medical laboratories • New York

INDENTURE, dated as of September 23, 2024, between LABORATORY CORPORATION OF AMERICA HOLDINGS, a Delaware corporation (the “Company”), and U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”):

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4.550% SENIOR NOTES DUE 2032 LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND LABCORP HOLDINGS INC. as Guarantor AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION as Trustee SECOND SUPPLEMENTAL INDENTURE DATED AS OF September 23, 2024
Second Supplemental Indenture • September 23rd, 2024 • Labcorp Holdings Inc. • Services-medical laboratories • New York

SECOND SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of September 23, 2024, among Laboratory Holdings Inc., a Delaware corporation (or its permitted successor) (“Parent Guarantor”), its wholly owned subsidiary, Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank Trust Company, National Association, as Trustee under the Indenture (the “Trustee”).

4.350% SENIOR NOTES DUE 2030 LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND LABCORP HOLDINGS INC. as Guarantor AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION as Trustee FIRST SUPPLEMENTAL INDENTURE DATED AS OF September 23, 2024
First Supplemental Indenture • September 23rd, 2024 • Labcorp Holdings Inc. • Services-medical laboratories • New York

FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of September 23, 2024, among Laboratory Holdings Inc., a Delaware corporation (or its permitted successor) (“Parent Guarantor”), its wholly owned subsidiary, Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank Trust Company, National Association, as Trustee under the Indenture (the “Trustee”).

4.800% SENIOR NOTES DUE 2034 LABORATORY CORPORATION OF AMERICA HOLDINGS as Issuer AND LABCORP HOLDINGS INC. as Guarantor AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION as Trustee THIRD SUPPLEMENTAL INDENTURE DATED AS OF September 23, 2024
Third Supplemental Indenture • September 23rd, 2024 • Labcorp Holdings Inc. • Services-medical laboratories • New York

THIRD SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of September 23, 2024, among Laboratory Holdings Inc., a Delaware corporation (or its permitted successor) (“Parent Guarantor”), its wholly owned subsidiary, Laboratory Corporation of America Holdings, a Delaware corporation (or its permitted successor) (the “Company”), and U.S. Bank Trust Company, National Association, as Trustee under the Indenture (the “Trustee”).

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