0001193125-24-248678 Sample Contracts

AMENDMENT NO. 2 TO THE EQUITY DISTRIBUTION AGREEMENT
Equity Distribution Agreement • October 31st, 2024 • Nurix Therapeutics, Inc. • Pharmaceutical preparations

This Amendment No. 2 to the Equity Distribution Agreement (this “Amendment”) is entered into as of the date first written above by Nurix Therapeutics, Inc., a Delaware corporation (the “Company”), and Piper Sandler & Co. (the “Agent”), that are parties to that certain Equity Distribution Agreement, dated August 4, 2021, and Amendment No. 1 thereto, dated July 11, 2024 (together, the “Original Agreement”).

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