0001193125-24-258595 Sample Contracts

AMENDED AND RESTATED SHARED SPACE ARRANGEMENT
Shared Space Arrangement • November 14th, 2024 • Omega Therapeutics, Inc. • Biological products, (no disgnostic substances) • Massachusetts

This Amended and Restated Shared Space Arrangement (this “Shared Space Arrangement”) is made and entered into effective as of the 18th day of November, 2024 (the “Effective Date”) by and between Omega Therapeutics, Inc., a Delaware corporation (“Licensor” or “Tenant”) with an address of 140 First Street, Ste 501, Cambridge, Massachusetts 02141, and Prologue Medicines, Inc. (formerly Flagship Labs 89, Inc.), a Delaware corporation (“Licensee” or “Space Occupant”), with an address of 140 First Street, Ste 502, Cambridge, Massachusetts 02141.

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Amended and Restated Employment Agreement
Separation Agreement and Release • November 14th, 2024 • Omega Therapeutics, Inc. • Biological products, (no disgnostic substances) • Massachusetts

This Amended and Restated Employment Agreement (this “Agreement”) is made by and between Omega Therapeutics, Inc., a Delaware corporation (together with any successor thereto, the “Company”), and Kaan Certel (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”) effective as of November 14, 2024 (the “Effective Date”).

Separation Agreement and Release
Separation Agreement and Release • November 14th, 2024 • Omega Therapeutics, Inc. • Biological products, (no disgnostic substances)

This Separation Agreement and Release (“Agreement”) is made by and between Mahesh Karande (“Executive”) and Omega Therapeutics, Inc. (the “Company”) (collectively referred to as the “Parties” or individually referred to as a “Party”). Capitalized terms used but not defined in this Agreement shall have the meanings set forth in the Employment Agreement (as defined below).

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