0001193805-10-003171 Sample Contracts

AMENDMENT NO. 1 TO DEPOSIT AGREEMENT
Deposit Agreement • December 30th, 2010 • JPMorgan Chase Bank, N.A. - ADR Depositary • Pharmaceutical preparations • New York

AMENDMENT NO. 1 dated as of December 30, 2010 (the "Amendment") to the Deposit Agreement dated as of April 15, 2008 (as amended from time to time, the "Deposit Agreement") among Evotec Aktiengesellschaft incorporated under the laws of the Federal Republic of Germany, and its successors (the "Company"), JPMorgan Chase Bank, N.A., as depositary (the "Depositary"), and all holders from time to time of ADRs issued thereunder.

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