0001200375-21-000056 Sample Contracts

AMENDMENT NO. 5 TO SITAGLIPTIN SUPPLY AGREEMENT
Sitagliptin Supply Agreement • November 5th, 2021 • Codexis, Inc. • Industrial organic chemicals

AMENDMENT NO. 5 TO SITAGLIPTIN CATALYST SUPPLY AGREEMENT (this “AMENDMENT”) is effective as of July 1, 2021 (the “AMENDMENT EFFECTIVE DATE”) by and between Codexis, Inc., a Delaware corporation, having a place of business at 200 Penobscot Drive, Redwood City, CA 94063 (“CODEXIS”) and Merck Sharp and Dohme Corp., having a place of business at One Merck Drive, Whitehouse Station, NJ 08889-0100. (“MERCK”)

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NINTH AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • November 5th, 2021 • Codexis, Inc. • Industrial organic chemicals • California

THIS NINTH AMENDMENT to Loan and Security Agreement (this “Amendment”) is made effective as of September 30, 2021 (the “Amendment Date”) and made by and among WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”) and CODEXIS, INC., a Delaware corporation (“Borrower”).

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