0001204459-05-000383 Sample Contracts

FIRST AMENDMENT TO "MANUFACTURING AND DISTRIBUTION LICENSE AGREEMENT"
Manufacturing and Distribution License Agreement • June 29th, 2005 • Alpharx Inc • Pharmaceutical preparations

This First Amendment is dated 22nd June 2005, and is made between AlphaRx International Holdings Limited ("AIH"), a corporation incorporated under the laws of the British Virgin Islands, and having its principal place of business at Unit A, 19/F Sang Woo Building, Nos. 227-228, Gloucester Road, Causeway Bay, Hong Kong and Alpha AP Inc. ("AAP"), a corporation incorporated under the laws of the British Virgin Islands, and having its principal office c/o Advance Pharmaceutical Co., Ltd., 2/F, 12 Dai Fu Street, Tai Po Industrial Estate, Tai Po, New Territories, Hong Kong.

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