0001213900-20-043049 Sample Contracts

AMENDMENT NO. 2 TO AT MARKET ISSUANCE SALES AGREEMENT
Market Issuance Sales Agreement • December 16th, 2020 • Alterity Therapeutics LTD • Pharmaceutical preparations • New York

Alterity Therapeutics Limited (formerly Prana Biotechnology Ltd) (the “Company”), B. Riley Securities, Inc. (formerly B. Riley FBR, Inc. (successor by merger to FBR Capital Markets & Co.)) (“B. Riley”) and JonesTrading Institutional Services LLC (“JonesTrading” and together with B. Riley, the “Agents”) are parties to that certain At Market Issuance Sales Agreement dated October 13, 2016, as amended on November 8, 2017 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement as follows:

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