CLINICAL MANUFACTURE AND SUPPLY AGREEMENTClinical Manufacture and Supply Agreement • September 27th, 2013 • Ocera Therapeutics, Inc. • Pharmaceutical preparations • New York
THIS CLINICAL MANUFACTURE AND SUPPLY AGREEMENT (the “Agreement”) is entered into as of December 22, 2005 (the “CSA Effective Date”), by and between OCERA THERAPEUTICS, INC. (“Ocera”), a Delaware corporation, having an address of 11622 El Camino Real, Suite 100, San Diego, CA 92130, United States of America, and KUREHA CORPORATION, a Japanese corporation (“Kureha”), having an address of 3-3-2, Nihonbashi Hama-cho, Chuo-ku, Tokyo 103-8552, Japan.
RESTATED LICENSE AGREEMENTLicense Agreement • September 27th, 2013 • Ocera Therapeutics, Inc. • Pharmaceutical preparations • New York
THIS RESTATED LICENSE AGREEMENT (the “Agreement”) is entered into as of March 6th, 2008 (the “Effective Date”) by and between KUREHA CORPORATION, a Japanese corporation (“Kureha”), having an address of 3-3-2, Nihonbashi-Hamacho, Chuo-ku, Tokyo 103-8552, Japan, and OCERA THERAPEUTICS, INC., a Delaware corporation (“Ocera”), having an address of 12651 High Bluff Drive, Suite 230, San Diego, CA 92130, United States of America.
AGREEMENTAgreement • September 27th, 2013 • Ocera Therapeutics, Inc. • Pharmaceutical preparations
This Agreement (hereinafter called “Agreement”) is made this April 5th, 2012 by and between Kureha Corporation, a Japanese corporation (hereinafter called “Kureha”), with its principal offices at 3-3-2, Nihonbashi-Hamacho, Chuo-ku, Tokyo 103-8552, Japan and Ocera Therapeutics, Inc., a Delaware corporation (hereinafter called “Ocera”), with its principal offices at 12651 High Bluff Drive, Suite 230, San Diego, CA 92130, the United States of America.
WHEREASLicense Agreement • September 27th, 2013 • Ocera Therapeutics, Inc. • Pharmaceutical preparations • England and Wales
certain milestone events, milestone payments and Ocera’s development and commercialization obligations, as set out in the amendments to the Amended and Restated Agreement attached as a Schedule to this Deed with effect from the date of
COMMERCIAL MANUFACTURE AND SUPPLY AGREEMENTManufacture and Supply Agreement • September 27th, 2013 • Ocera Therapeutics, Inc. • Pharmaceutical preparations • New York
THIS COMMERCIAL MANUFACTURE AND SUPPLY AGREEMENT (the “Agreement”) is entered into as of November 1st, 2007 (the “Effective Date”), by and between OCERA THERAPEUTICS, INC. (“Ocera”), a Delaware corporation, having an address of 12651 High Bluff Drive, Suite 230, San Diego, CA 92130, United States of America, and KUREHA CORPORATION, a Japanese corporation (“Kureha”), having an address of 3-3-2, Nihonbashi Hama-cho, Chuo-ku, Tokyo 103-8552, Japan.
