0001274644-15-000049 Sample Contracts

OCERA THERAPEUTICS, INC. $25,000,000 SALES AGREEMENT
Sales Agreement • August 10th, 2015 • Ocera Therapeutics, Inc. • Pharmaceutical preparations • New York

Ocera Therapeutics, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows:

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SECOND AMENDMENT TO LEASE AGREEMENT
Lease Agreement • August 10th, 2015 • Ocera Therapeutics, Inc. • Pharmaceutical preparations

This Second Amendment to Lease Agreement (“Second Amendment”) is entered into on June 5, 2015 (“Effective Date”) by and between James Campbell Company LLC, a Delaware limited liability company (“Landlord”) and Ocera Therapeutics, Inc., a Delaware corporation f/k/a Tranzyme, Inc. (“Tenant”).

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