0001279569-16-004420 Sample Contracts

AMENDMENT NO. 4 TO SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 30th, 2016 • Cipher Pharmaceuticals Inc • Pharmaceutical preparations • New York

This AMENDMENT NO. 4 TO SECURITIES PURCHASE AGREEMENT is entered into as of September 29, 2016 (this “Amendment”), among CIPHER PHARMACEUTICALS INC., an Ontario corporation (the “Issuer”), the Guarantors party hereto, ATHYRIUM OPPORTUNITIES II ACQUISITION LP, as a Purchaser, the other Purchasers party hereto (collectively, the “Purchasers”) and ATHYRIUM OPPORTUNITIES II ACQUISITION LP, as Collateral Agent.

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