0001299933-05-001869 Sample Contracts

April 19, 2005 Steven B. Engle La Jolla Pharmaceutical Company 6455 Nancy Ridge Drive San Diego, California 92121 Dear Steve,
La Jolla Pharmaceutical Co • April 22nd, 2005 • Biological products, (no disgnostic substances)

La Jolla Pharmaceutical Company (the “Company”) believes that you are able to make a serious and valuable contribution to the Company and help the Company achieve success in the strategic objects identified herein. Accordingly, in order retain your services and to incentivize you to continue as an employee, subject to the terms of this letter agreement (this “Agreement”), the Company hereby offers to pay to you (i) a retention bonus and (ii) certain success bonuses, the payment of which are conditioned upon the Company’s achievement of the strategic objectives identified herein. The bonuses will be calculated with regard to your current annual base salary (your “Salary”).

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April 19, 2005 Bruce K. Bennett La Jolla Pharmaceutical Company 6455 Nancy Ridge Drive San Diego, California 92121 Dear Bruce,
La Jolla Pharmaceutical Co • April 22nd, 2005 • Biological products, (no disgnostic substances)

La Jolla Pharmaceutical Company (the “Company”) believes that you are able to make a serious and valuable contribution to the Company and help the Company achieve success in the strategic objects identified herein. Accordingly, in order retain your services and to incentivize you to continue as an employee, subject to the terms of this letter agreement (this “Agreement”), the Company hereby offers to pay to you (i) a retention bonus and (ii) certain success bonuses, the payment of which are conditioned upon the Company’s achievement of the strategic objectives identified herein. The bonuses will be calculated with regard to your current annual base salary (your “Salary”).

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