0001299933-05-004249 Sample Contracts

SECOND AMENDMENT TO THE COLLABORATION AND LICENSE AGREEMENT
The Collaboration and License Agreement • August 19th, 2005 • Memory Pharmaceuticals Corp • Pharmaceutical preparations

This SECOND AMENDMENT TO THE COLLABORATION AND LICENSE AGREEMENT (this “Second Amendment”) is executed to be effective this 18th day of August 2005, by and between Memory Pharmaceuticals Corp. (“Memory”), and F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc. (collectively, “Roche”) (Memory and Roche are hereinafter referred to individually as a “Party” and collectively as the “Parties”). All capitalized terms used herein and not defined shall have the meanings set forth in the Agreement (as defined below).

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