Exhibit 2.1 AMENDMENT NO. 1 TO AMENDED AND RESTATED AGREEMENT AND PLAN OF MERGER (this "Amendment") dated as of January 11, 2006, by and among JOHNSON & JOHNSON, a New Jersey corporation ("Parent"), SHELBY MERGER SUB, INC., an Indiana corporation and...Agreement and Plan of Merger • January 12th, 2006 • Guidant Corp • Surgical & medical instruments & apparatus • Indiana
