0001356576-13-000029 Sample Contracts

FIRST SUPPLEMENTAL INDENTURE
First Supplemental Indenture • October 24th, 2013 • Supernus Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS SUPPLEMENTAL INDENTURE, dated as of October 24, 2013, to the Indenture (as defined below), is hereby entered into by and between Supernus Pharmaceuticals, Inc., a Delaware corporation (the “Issuer”), and U.S. Bank National Association, a national banking association (the “Trustee”) (this “Supplemental Indenture”).

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