0001375151-13-000005 Sample Contracts

FIRST AMENDMENT TO BATTELLE/ZOGENIX CO-MARKETING AND OPTION AGREEMENT
Marketing and Option Agreement • May 9th, 2013 • Zogenix, Inc. • Pharmaceutical preparations

This First Amendment (“Amendment”) to the Co-Marketing and Option Agreement dated March 29, 2012 (“Agreement”) is made and entered into as of the 21st day of March, 2013 and is by and between Battelle Memorial Institute (“Battelle”) and Zogenix, Inc. (“Zogenix”) (Battelle and Zogenix are individually referred to as a “Party” and collectively referred to as the “Parties”).

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AMENDMENT NO. 1 TO DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • May 9th, 2013 • Zogenix, Inc. • Pharmaceutical preparations

THIS AMENDMENT No. 1 TO DEVELOPMENT AND LICENSE AGREEMENT (the “Amendment”) is entered into on March 18, 2013 (the “Execution Date”) and made retroactive to January 1, 2013 (the “Effective Date of the Amendment”), by and between DURECT Corporation (“Durect”) and Zogenix, Inc. (“Zogenix”).

SECOND AMENDMENT TO LICENSE AGREEMENT
License Agreement • May 9th, 2013 • Zogenix, Inc. • Pharmaceutical preparations • New York

This Second Amendment to the License Agreement (as defined below) (the "Second Amendment") is made and entered into as of 12th day of March, 2013 (“Second Amendment Effective Date”).

Manufacturing Services Agreement Between Patheon UK Limited And Zogenix Inc.
Manufacturing Services Agreement • May 9th, 2013 • Zogenix, Inc. • Pharmaceutical preparations • England

THIS MANUFACTURING SERVICES AGREEMENT (the “Agreement”) made as of this February 28, 2013 (“Execution Date”), with an effective date of November 1, 2013 (“Effective Date”).

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