0001390478-17-000036 Sample Contracts

SEPARATION AGREEMENT AND GENERAL RELEASE
Separation Agreement • May 10th, 2017 • Galena Biopharma, Inc. • Pharmaceutical preparations • California

This Separation Agreement and General Release (this "Agreement") is hereby entered into by and between Mark W. Schwartz, Ph.D., an individual (the "Employee"), and Galena Biopharma, Inc., on behalf of itself and all of its affiliated entities, specifically including Apthera, Inc. and Mills Pharmaceuticals, LLC (collectively, the "Company").

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February 23, 2017 Stephen Ghiglieri [Address] Dear Mr. Ghiglieri:
Retention Agreement • May 10th, 2017 • Galena Biopharma, Inc. • Pharmaceutical preparations

This Retention Agreement establishes the terms of the retention payment during your continued employment with Galena Biopharma, Inc. (“Galena” or “Company”), as the Company seeks to pursue strategic alternatives for the Company.

February 23, 2017 Bijan Nejadnik, M.D. [Address] Dear Dr. Nejadnik:
Retention Agreement • May 10th, 2017 • Galena Biopharma, Inc. • Pharmaceutical preparations

This Retention Agreement establishes the terms of the retention payment during your continued employment with Galena Biopharma, Inc. (“Galena” or “Company”), as the Company seeks to pursue strategic alternatives for the Company.

February 23, 2017 John Burns [Address] Dear Mr. Burns:
Retention Agreement • May 10th, 2017 • Galena Biopharma, Inc. • Pharmaceutical preparations

This Retention Agreement establishes the terms of the retention payment during your continued employment with Galena Biopharma, Inc. (“Galena” or “Company”), as the Company seeks to pursue strategic alternatives for the Company.

February 23, 2017 Thomas J. Knapp [Address] Dear Mr. Knapp:
Retention Agreement • May 10th, 2017 • Galena Biopharma, Inc. • Pharmaceutical preparations

This Retention Agreement establishes the terms of the retention payment during your continued employment with Galena Biopharma, Inc. (“Galena” or “Company”), as the Company seeks to pursue strategic alternatives for the Company.

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