0001399529-19-000005 Sample Contracts

SHARE ISSUANCE AGREEMENT
Share Issuance Agreement • March 13th, 2019 • Dicerna Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS SHARE ISSUANCE AGREEMENT (this “Agreement”), is made as of October 25, 2018, by and between Eli Lilly and Company, an Indiana corporation (the “Share Acquiror”), and Dicerna Pharmaceuticals, Inc., a Delaware corporation (the “Company”).

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SHARE ISSUANCE AGREEMENT
Share Issuance Agreement • March 13th, 2019 • Dicerna Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS SHARE ISSUANCE AGREEMENT (this “Agreement”), is made as of October 22, 2018, by and between Alexion Pharmaceuticals, Inc., a Delaware corporation (the “Share Acquiror”), and Dicerna Pharmaceuticals, Inc., a Delaware corporation (the “Company”).

COLLABORATIVE RESEARCH AND LICENSE AGREEMENT between Alexion Pharma Holding Unlimited Company Dicerna Pharmaceuticals Inc. and Dicerna Cayman DATED OCTOBER 22, 2018
Collaborative Research and License Agreement • March 13th, 2019 • Dicerna Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

THIS COLLABORATIVE RESEARCH AND LICENSE AGREEMENT (this “Agreement”) is entered into as of October 22, 2018 (the “Effective Date”) by and among ALEXION PHARMA HOLDING UNLIMITED COMPANY, an unlimited liability company incorporated under the laws of Ireland with a principal place of business at [***] (“ALEXION”), DICERNA PHARMACEUTICALS INC., a corporation organized and existing under the laws of Delaware with a principal place of business at 87 Cambridgepark Drive, Cambridge, MA 02140 (“DICERNA PHARMA”), and Dicerna Cayman, an exempted company incorporated with limited liability under the laws of the Cayman Islands (“DICERNA CAYMAN”, and together with DICERNA PHARMA, “DICERNA”). ALEXION and DICERNA are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • March 13th, 2019 • Dicerna Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS COLLABORATION AND LICENSE AGREEMENT (the “Agreement”), effective as of October 25, 2018 (the “Effective Date”), is by and between ELI LILLY AND COMPANY, a corporation organized and existing under the laws of Indiana, with its principal business office located at Lilly Corporate Center, Indianapolis, Indiana 46285, U.S.A. (“Lilly”), on the one hand, and DICERNA PHARMACEUTICALS INC., a corporation organized and existing under the laws of Delaware, with its principal place of business at 87 Cambridgepark Drive, Cambridge, Massachusetts 02140, U.S.A. (“Dicerna US”), and DICERNA CAYMAN, an exempted company incorporated with limited liability under the laws of the Cayman Islands (“Dicerna Cayman” and, collectively with Dicerna US, “Dicerna”), on the other hand. Dicerna and Lilly are each referred to individually as a “Party” and together as the “Parties”.

Contract number: 43085381
Additional Target Agreement • March 13th, 2019 • Dicerna Pharmaceuticals Inc • Pharmaceutical preparations • New York

This additional target agreement (the “ATA”) is made on December 31, 2018 (the “Effective Date”) under the terms and conditions herein by and between Boehringer Ingelheim International GmbH having a principal place of business at Binger Strasse 173, 55216 Ingelheim, Germany, (hereinafter referred to as “BOEHRINGER”), and Dicerna Pharmaceuticals Inc., 87 Cambridgepark Drive, Cambridge, MA 02140, USA (hereinafter referred to as “DICERNA”).

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