0001400482-17-000031 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • March 15th, 2017 • Kubota Pharmaceutical Holdings Co LTD • Pharmaceutical preparations • Washington

This Employment Agreement (the "Agreement") is made and entered into effective as of August 17, 2015 (the "Effective Date"), by and between Lukas Scheibler (the "Executive") and Acucela Inc. (the "Company").

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SEPARATION AGREEMENT AND RELEASE
Separation Agreement • March 15th, 2017 • Kubota Pharmaceutical Holdings Co LTD • Pharmaceutical preparations • California

This Separation Agreement and Release (the "Agreement") is made by and between George Lasezkay (the "Executive") and Acucela Inc. (the "Company") (collectively referred to as the "Parties" or individually referred to as a "Party").

CONSULTING AGREEMENT
Consulting Agreement • March 15th, 2017 • Kubota Pharmaceutical Holdings Co LTD • Pharmaceutical preparations

THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of July 11, 2016 (“Effective Date”) between ACUCELA INC., a Washington corporation, having an address at 1301 Second Avenue, Suite 4200, Seattle, WA 98101 (“Company”) and GEORGE LASEZKAY, having an address at 3703 Old Charlotte Pike, Franklin, TN 37069 (“Consultant”). Company desires to retain Consultant to perform certain consulting activities as described below on Exhibit A hereto, and Consultant desires to serve as a consultant to Company and be available to engage in such activities under the terms of this Agreement.

THIRD AMENDMENT TO LEASE [Nexus Canyon Park LLC / Acucela Inc.]
Lease • March 15th, 2017 • Kubota Pharmaceutical Holdings Co LTD • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (this “Third Amendment”) is effective as of November 9, 2016 (“Effective Date”) by and between NEXUS CANYON PARK LLC, a Delaware limited liability company, and ACUCELA INC., a Washington corporation, “Landlord” and “Tenant”, respectively, under that certain Lease dated February 13, 2006 as Amended by a First Amendment to Lease dated August 15, 2011 and a Second Amendment to Lease dated September 1, 2014 (as amended, the “Lease”) for the Premises described in Section 1.1 of the Lease, consisting of approximately 17,488 square feet of Rentable Area designated as Suite 120 in the Building located at 21720 23rd Drive S.E., Bothell, Washington, on real property legally described as Tract 21-B of Canyon Park Business Center Binding Site Plan recorded under Recording No. 9708195005, records of Snohomish County, Washington, being a portion of the Northwest Quarter of Section 29, Township 27 North, Range 5 East, W.M.

SUB-SUBLEASE AGREEMENT
Sub-Sublease Agreement • March 15th, 2017 • Kubota Pharmaceutical Holdings Co LTD • Pharmaceutical preparations • Washington

This Sub-Sublease Agreement (the “Sub-Sublease Agreement”) is entered as of January 12, 2016 (the “Effective Date”) between Acucela Inc., a Washington corporation (“Sublessor”) and Zillow, Inc., a Washington corporation (“Sublessee”).

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