0001437749-16-037980 Sample Contracts

COMMON STOCK PURCHASE WARRANT sophiris bio inc.
Common Stock Purchase Warrant • August 23rd, 2016 • Sophiris Bio Inc. • Pharmaceutical preparations • New York

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant” and the term “Warrants” below refers to this Warrant and all other warrants to purchase Common Stock originally issued by the Company on the date hereof) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to the close of business on the five year anniversary of the Initial Exercise Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from Sophiris Bio Inc., a British Columbia corporation (the “Company”), up to shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

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6,500,000 Common Shares and Warrants to Purchase 4,875,000 Common Shares SOPHIRIS BIO INC. PURCHASE AGREEMENT
Common Stock Purchase Warrant • August 23rd, 2016 • Sophiris Bio Inc. • Pharmaceutical preparations • New York

Sophiris Bio Inc., a British Colombia corporation (and together with its subsidiaries, the “Company”) proposes to sell to the several Underwriters named in Schedule I hereto (the “Underwriters”) an aggregate of (i) 6,500,000 shares (the “Firm Shares”) of Common Shares, no par value per share (the “Common Shares”), of the Company and (ii) warrants to purchase up to 4,875,000 Common Shares in the form set forth in Exhibit A (each, a “Warrant”). Each Firm Share is being sold together with a Warrant to purchase 0.75 Common Shares at an exercise price of $4.00 per whole Common Share. The Company has also granted to the Underwriters an option to purchase up to 975,000 additional Common Shares (“Option Shares”) with additional Warrants to purchase up to 731,250 Common Shares (“Option Warrants”), on the terms and for the purposes set forth in Section 3 hereof. The Firm Shares, Option Shares, Warrants and Option Warrants are collectively called the “Securities.” The Common Shares underlying the

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