0001445305-12-000499 Sample Contracts

PERKINELMER, INC. $500,000,000 5.00% Senior Notes due 2021 SECOND SUPPLEMENTAL INDENTURE Dated as of December 22, 2011 to Indenture Dated as of October 25, 2011
Second Supplemental Indenture • February 28th, 2012 • Perkinelmer Inc • Laboratory analytical instruments • New York

This SECOND SUPPLEMENTAL INDENTURE, dated as of December 22, 2011 (this “Supplemental Indenture”), to the Indenture, dated as of October 25, 2011 (the “Base Indenture”), as supplemented by the First Supplemental Indenture, dated as of October 25, 2011 (the “First Supplemental Indenture”) (such Base Indenture, as supplemented by the First Supplemental Indenture, the “Existing Indenture”), between PERKINELMER, INC., a Massachusetts corporation (the “Company”), and U.S. Bank National Association, as trustee (the “Trustee”) (the Existing Indenture, as supplemented by this Supplemental Indenture, the “Indenture”).

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