0001453687-20-000104 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • September 3rd, 2020 • Selecta Biosciences Inc • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of August 31, 2020 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender and SILICON VALLEY BANK, a California corporation with an office located at 3003 Tasman Drive, Santa Clara, CA 95054 (“Bank” or “SVB”) (each a “Lender” and collectively, the “Lenders”), and SELECTA BIOSCIENCES, INC., a Delaware corporation with offices located at 65 Grove Street, Suite 101, Watertown, MA 02472 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

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SELECTA BIOSCIENCES, INC. Watertown, MA 02472
Loan Agreement • September 3rd, 2020 • Selecta Biosciences Inc • Pharmaceutical preparations • California

This letter (this “Side Letter”) will confirm our agreement that, in connection with the transactions contemplated by that certain Loan and Security Agreement of even date herewith (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “Loan Agreement”), by and among SELECTA BIOSCIENCES, INC., a Delaware Corporation with offices located at 65 Grove Street, Watertown, MA 02472 (the “Company”), OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders from time to time party thereto, including Oxford in its capacity as a Lender and SILICON VALLEY BANK, a California corporation with an office located at 3003 Tasman Drive, Santa Clara, CA 95054 (“Bank” or “SVB”) (each a “Lender” and collectively, the “Lenders”), the Company agrees to issue Warrants to purchase capital stock of the Co

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