0001485003-16-000068 Sample Contracts

CONSENT AND THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • March 25th, 2016 • Eleven Biotherapeutics, Inc. • Pharmaceutical preparations • Massachusetts

This CONSENT AND THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Amendment” or the “Third Amendment”) is entered into this 4th day of December, 2015, by and between SILICON VALLEY BANK (“Bank”) and ELEVEN BIOTHERAPEUTICS, INC., a Delaware corporation (“Borrower”).

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AMENDMENT # 1 TO LICENSE AGREEMENT
License Agreement • March 25th, 2016 • Eleven Biotherapeutics, Inc. • Pharmaceutical preparations

This Amendment # 1 to License Agreement (the “First Amendment”) is effective as of December 22, 2015 (the “First Amendment Effective Date”) and amends the License Agreement made effective as of July 13, 2010 (“Agreement”) by and between Eleven Biotherapeutics, Inc. (“LICENSEE”) and The Schepens Eye Research Institute, Inc. (“LICENSOR”).

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