0001493152-17-013761 Sample Contracts

NOTE PURCHASE AGREEMENT
Note Purchase Agreement • November 24th, 2017 • Marina Biotech, Inc. • Pharmaceutical preparations • New York

THIS NOTE PURCHASE AGREEMENT (“Agreement”) is made as of November 22, 2017 (the “Execution Date”) by and between Marina Biotech, Inc., a Delaware corporation (the “Company”), and River Charitable Remainder Unit Trust, FBO Isaac Blech, July 20, 1987, Isaac Blech Trustee (the “Lender”). Capitalized terms used but not defined herein shall have the respective meanings ascribed to such terms in the Note (as defined below).

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STOCK OPTION AGREEMENT
Stock Option Agreement • November 24th, 2017 • Marina Biotech, Inc. • Pharmaceutical preparations • Delaware

THIS STOCK OPTION AGREEMENT (this “Agreement”) is entered into and effective as of November 22, 2017 (the “Grant Date”) by and between Marina Biotech, Inc., a Delaware corporation (the “Company”), and Isaac Blech (“Optionee”).

SECURITY AGREEMENT
Security Agreement • November 24th, 2017 • Marina Biotech, Inc. • Pharmaceutical preparations • New York

This SECURITY AGREEMENT (this “Agreement”), dated as of November 22, 2017, among Marina Biotech, Inc., a Delaware corporation (the “Company”), IthenaPharma, Inc., a Delaware corporation and a wholly-owned subsidiary of the Company (“Ithena”), Cequent Pharmaceuticals, Inc., a Delaware corporation and a wholly-owned subsidiary of the Company (“CPI”), and MDRNA Research, Inc., a Delaware corporation and a wholly-owned subsidiary of the Company (“Research” and, collectively with the Company, Ithena and CPI, the “Grantors” and each, individually, a “Grantor”), and River Charitable Remainder Unit Trust, FBO Isaac Blech, July 20, 1987, Isaac Blech Trustee (the “Purchaser”) under that certain Note Purchase Agreement dated as of the date hereof between the Company and the Purchaser (as it may be amended, restated, supplemented, replaced or otherwise modified from time to time, the “Purchase Agreement).

INTELLECTUAL PROPERTY SECURITY AGREEMENT
Intellectual Property Security Agreement • November 24th, 2017 • Marina Biotech, Inc. • Pharmaceutical preparations • New York

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (this “Agreement”), dated as of November 22, 2017, is made by MARINA BIOTECH, INC., a Delaware corporation (the “Company”), IthenaPharma, Inc., a Delaware corporation (“Ithena”), Cequent Pharmaceuticals, Inc., a Delaware corporation (“CPI”), and MDRNA RESEARCH, INC., a Delaware corporation (“Research” and, collectively with the Company, Ithena and CPI, “Grantors” and each, individually, “Grantor”), in favor of River Charitable Remainder Unit Trust, FBO Isaac Blech, July 20, 1987, Isaac Blech Trustee (the “Purchaser”).

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