0001493152-22-006119 Sample Contracts

UNDERWRITING AGREEMENT between OKYO PHARMA LIMITED and THINKEQUITY LLC as Representative of the Several Underwriters OKYO PHARMA LIMITED
Underwriting Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances) • New York

The undersigned, OKYO Pharma Limited a company with limited liability formed under the laws of Guernsey (collectively with its subsidiaries and affiliates, including, without limitation, all entities disclosed or described in the Registration Statement (as hereinafter defined) as being subsidiaries or affiliates of OKYO Pharma Limited, the “Company”), hereby confirms its agreement (this “Agreement”) with ThinkEquity LLC (hereinafter referred to as “you” (including its correlatives) or the “Representative”) and with the other underwriters named on Schedule 1 hereto for which the Representative is acting as representative (the Representative and such other underwriters being collectively called the “Underwriters” or, individually, an “Underwriter”) as follows:

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Re: EMPLOYMENT AGREEMENT
Employment Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances) • New York

This Employment Agreement (the “Agreement”) between you (referred to hereinafter as the “Executive”) and OKYO Pharma Limited, a company incorporated in Guernsey, Channel Islands (the “Company”) sets forth the terms and conditions that shall govern the period of Executive’s continued employment with the Company (referred to hereinafter as “Employment” or the “Employment Period”). Your employing entity for the purposes of the Employment will be OKYO Pharma US Inc., a wholly owned subsidiary of the Company.

AMENDMENT No. 1 TO COLLABORATION AGREEMENT BETWEEN TUFTS MEDICAL CENTER, INC AND OKYO PHARMA LIMITED
Collaboration Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances)

THIS AMENDMENT is entered into as of the date of last signature below by and between Tufts Medical Center, Inc., a not-for-profit tax-exempt corporation organized under the laws of the Commonwealth of Massachusetts with its principal place of business at 800 Washington Street, Boston, MA 02111 (“Tufts MC”), and Okyo Pharma Limited, a limited liability company incorporated and registered in Guernsey whose registered office and principal place of business is at Martello Court, Admiral Park, St. Peter Port, Guernsey GYI 3HB (“OKYO”).

Dated June 4, 2018 - and - COLLABORATION AGREEMENT FOR THE PROPOSED “CHEMERIN” PROGRAM
Collaboration Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances) • New York
Dated August 6th, 2019 - and - COLLABORATION AGREEMENT FOR THE PROPOSED CORNEAL NEUROPATHIC PAIN PROGRAM COOLEY (UK) LLP, DASHWOOD, 69 OLD BROAD STREET, LONDON EC2M 1QS, UK
Collaboration Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances) • New York
LICENSE AGREEMENT
License Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances) • Massachusetts

This License Agreement (“Agreement”) is made effective as of May 1, 2018 (“Effective Date”) by and between on the one hand Tufts Medical Center, Inc., 800 Washington Street, Boston, MA 02111 (the “Licensor”), and , OKYO PHARMA LIMITED, whose registered office is at Martello Court, Admiral Park, St. Peter Port, Guernsey GY1 3HB (“Licensee’’). Licensor and Licensee are each hereafter referred to individually as a “Party’’ and together as the “Parties.”

FIRST AMENDMENT TO THE LICENSE AND SUBLICENSE AGREEMENT BY AND BETWEEN ON TARGET THERAPEUTICS LLC AND OKYO PHARMA LIMITED
License and Sublicense Agreement • March 4th, 2022 • OKYO Pharma LTD • Biological products, (no disgnostic substances)

This FIRST AMENDMENT TO THE LICENSE AND SUBLICENSE AGREEMENT (“First Amendment”) is dated as of March 25, 2021 (the “First Amendment Effective Date”) by and between On Target Therapeutics, LLC, 15 Wynnewood Road, Wellesley, MA 02481 and (“On Target”) and OKYO Pharma Limited, Martello Court, Admiral Park, St. Peter Port, Guernsey, GY1 3HB (“OKYO”).

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