0001493152-24-045671 Sample Contracts

THIRD AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

THIS THIRD AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT (this “Amendment”) is made and entered into as of November 13, 2024 (“Amendment Effective Date”), by and between CEDARS-SINAI MEDICAL CENTER, a California nonprofit public benefit corporation (“CSMC”) and KAIROS PHARMA, LTD., a California corporation (“Licensee”), under the following circumstances:

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PURCHASE AGREEMENT
Purchase Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations • New York

THIS PURCHASE AGREEMENT (this “Agreement”), dated as of November 12, 2024 (the “Effective Date”), is made by and between HELENA GLOBAL INVESTMENT OPPORTUNITIES I LTD. (the “Investor”), and KAIROS PHARMA, LTD., a Delaware corporation (the “Company”).

FOURTH AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

THIS FOURTH AMENDMENT TO EXCLUSIVE LICENSE AGREEMENT (this “Amendment”) is made and entered into as of November 13, 2024 (“Amendment Effective Date”), by and between CEDARS-SINAI MEDICAL CENTER, a California nonprofit public benefit corporation (“CSMC”) and ENVIRO THERAPEUTICS, INC., a California corporation (“Licensee”), under the following circumstances:

SECOND CONVERSION AGREEMENT
Conversion Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations • California

This SECOND CONVERSION AGREEMENT (this “Agreement”) is made and entered into as of November 13, 2024 (“Effective Date”), by and between Cedars-Sinai Medical Center, a California nonprofit public benefit corporation (“Cedars-Sinai”), on the one hand, and Kairos Pharma, Ltd., a Delaware corporation (“Kairos”), and Enviro Therapeutics, Inc., a California corporation and wholly-owned subsidiary of Kairos (“Enviro” and together with Kairos, the “Company”), on the other hand.

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

This Amendment No. 1 (the “Amendment”) to the Employment Agreement (the “Original Employment Agreement”), originally dated September 27, 2023, is hereby entered into as of the 11th day of November 2024, by and between Kairos Pharma, Ltd., a Delaware corporation (the “Company”), and Neil Bhowmick (the “Executive”). Terms not otherwise defined herein shall have the meaning set forth in the Original Employment Agreement

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

This Amendment No. 1 (the “Amendment”) to the Employment Agreement (the “Original Employment Agreement”), originally dated September 27, 2023, is hereby entered into as of the 11th day of November 2024, by and between Kairos Pharma, Ltd., a Delaware corporation (the “Company”), and Ramachandran Murali (the “Executive”). Terms not otherwise defined herein shall have the meaning set forth in the Original Employment Agreement

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

This Amendment No. 1 (the “Amendment”) to the Employment Agreement (the “Original Employment Agreement”), originally dated September 27, 2023, is hereby entered into as of the 11th day of November 2024, by and between Kairos Pharma, Ltd., a Delaware corporation (the “Company”), and John Yu (the “Executive”). Terms not otherwise defined herein shall have the meaning set forth in the Original Employment Agreement

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • November 14th, 2024 • Kairos Pharma, LTD. • Pharmaceutical preparations

This Amendment No. 1 (the “Amendment”) to the Employment Agreement (the “Original Employment Agreement”), originally dated September 27, 2023, is hereby entered into as of the ____ day of November 2024, by and between Kairos Pharma, Ltd., a Delaware corporation (the “Company”), and Doug Samuelson (the “Executive”). Terms not otherwise defined herein shall have the meaning set forth in the Original Employment Agreement

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