0001532063-14-000006 Sample Contracts

TENTH SUPPLEMENTAL INDENTURE
Tenth Supplemental Indenture • February 20th, 2014 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Tenth Supplemental Indenture (this “Tenth Supplemental Indenture”), dated as of October 21, 2013, among Express Scripts, Inc., a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), United BioSource Holdings, Inc., a Delaware corporation, and Express Scripts Pharmacy, Inc. (each an “Additional Guarantor”, and together the “Additional Guarantors”), and Union Bank, N.A., a national banking association, as trustee under the indenture referred to below (the “Trustee”).

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TENTH SUPPLEMENTAL INDENTURE
Tenth Supplemental Indenture • February 20th, 2014 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Tenth Supplemental Indenture (this “Tenth Supplemental Indenture”), dated as of October 21, 2013, among Express Scripts Holding Company (formerly Aristotle Holding, Inc.), a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), United BioSource Holdings, Inc., a Delaware corporation, and Express Scripts Pharmacy, Inc. (each an “Additional Guarantor”, and together the “Additional Guarantors”), and Wells Fargo Bank, National Association, as trustee under the indenture referred to below (the “Trustee”).

THIRD SUPPLEMENTAL INDENTURE
Third Supplemental Indenture • February 20th, 2014 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Supplemental Indenture (this “Third Supplemental Indenture”), dated as of October 21, 2013, among Medco Health Solutions, Inc., a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), United BioSource Holdings, Inc., a Delaware corporation, and Express Scripts Pharmacy, Inc. (each an “Additional Guarantor”, and together the “Additional Guarantors”), and U.S. Bank Trust National Association, as trustee under the indenture referred to below (the “Trustee”).

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