0001558370-17-000831 Sample Contracts

Change Order 6 to Clinical Services Agreement
RedHill Biopharma Ltd. • February 23rd, 2017 • Pharmaceutical preparations

This Change Order 6 (“Change Order”) to the Clinical Services Agreement signed 15 June 2011 (“Clinical Services Agreement”), is by and among:

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Change Order 7 to Clinical Services Agreement
Milestone Original Agreement • February 23rd, 2017 • RedHill Biopharma Ltd. • Pharmaceutical preparations

This Change Order 7 (“Change Order”) to the Clinical Services Agreement signed 15 June 2011 (“Clinical Services Agreement”), is by and among:

THE SYMBOL "[****]" DENOTES PLACES WHERE PORTIONS OF THIS DOCUMENT HAVE BEEN OMIITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT. SUCH MATERIAL HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION Change Order 5.1 to Clinical...
Milestone Original Agreement • February 23rd, 2017 • RedHill Biopharma Ltd. • Pharmaceutical preparations

This Change Order 5.1 (“Change Order”) to the Clinical Services Agreement signed 15 June 2011 (“Clinical Services Agreement”), is by and among:

strictly confidential - EXECUTION VERSION THE SYMBOL "[****]" DENOTES PLACES WHERE PORTIONS OF THIS DOCUMENT HAVE BEEN OMIITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT. SUCH MATERIAL HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE...
Exclusive Commercialization Agreement • February 23rd, 2017 • RedHill Biopharma Ltd. • Pharmaceutical preparations • New York

THIS EXCLUSIVE COMMERCIALIZATION AGREEMENT (the “Agreement”) is made and entered into as of December 30, 2016 (the “Effective Date”), by and between CONCORDIA PHARMACEUTICALS INC., a société à responsabilité limitée (private limited liability company) duly continued and validly existing under the laws of the Grand-Duchy of Luxembourg, having its registered office at 8-10 Avenue de la Gare – L-1610 Luxembourg, Grand-Duchy of Luxembourg, and registered with the Registre de commerce et des sociétés, Luxembourg (register of trade and companies) under number B 200 344, by way of its Barbados branch, carrying on business at 5 Canewood Business Centre, St. Michael, Barbados, BB 11005 (“Concordia”) and REDHILL BIOPHARMA LTD., an Israeli company, having a place of business at 21 Ha'arba'a Street, Tel-Aviv, Israel (“RedHill”). RedHill and Concordia each may be referred to herein individually as a “Party,” or collectively as the “Parties”.

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