0001558370-17-003785 Sample Contracts

CONFIDENTIAL Execution Copy
Confidential Execution • May 8th, 2017 • Ironwood Pharmaceuticals Inc • Pharmaceutical preparations • New York

[**] = Portions of this exhibit have been omitted pursuant to a confidential treatment request. An unredacted version of this exhibit has been filed separately with the Commission.

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COMMERCIAL AGREEMENT BY AND AMONG ALLERGAN USA, INC., Ironwood Pharmaceuticals, Inc. AND Forest Laboratories, LLC
Commercial Agreement • May 8th, 2017 • Ironwood Pharmaceuticals Inc • Pharmaceutical preparations • New York

This COMMERCIAL AGREEMENT (this “Agreement”), is made and dated as of January 31, 2017 (the “Effective Date”), by and among Allergan USA, Inc., a corporation duly organized and existing under the Applicable Laws of the State of Delaware, and having a principal place of business at Morris Corporate Center III, 400 Interpace Parkway, Parsippany, New Jersey 07054 (“Allergan”), Ironwood Pharmaceuticals, Inc., a corporation duly organized and existing under the Applicable Laws of the State of Delaware, and having a principal place of business at 301 Binney Street, Cambridge, Massachusetts 02142 (“Ironwood”), and, for purposes of Section 3.1, Forest Laboratories, LLC (as successor-in-interest to Forest Laboratories, Inc.), a limited liability company duly organized and existing under the Applicable Laws of the State of Delaware, and having a principal place of business at Morris Corporate Center III, 400 Interpace Parkway, Parsippany, New Jersey 07054 (“Forest”). Allergan and Ironwood are so

TWELFTH AMENDMENT TO LEASE
Lease • May 8th, 2017 • Ironwood Pharmaceuticals Inc • Pharmaceutical preparations

THIS TWELFTH AMENDMENT TO LEASE (this “Amendment”) is entered into as of this 30th day of March, 2017 (the “Execution Date”), by and between BMR-ROGERS STREET LLC, a Delaware limited liability company (“Landlord,” as successor-in-interest to Rogers Street, LLC (“Original Landlord”)), and IRONWOOD PHARMACEUTICALS, INC., a Delaware corporation (“Tenant,” formerly known as Microbia, Inc.).

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